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8. · A tumor can place direct pressure on the structure of the back, most often in the mid to upper back rather than lower back. 20. . Other signs may include. A French study of workers across various professions found about 9% of men and 17% of women reported at least some. · Symptoms. · There is usually no pain involved, especially when the lymphoma is in the early stage of development One of the earliest signs I had was 6 months prior; I had itching without a rash on both of my lower legs, inner thighs and the back of my arms with some facial itching as well In February I noticed I was getting sick and decided to go see a doctor Some people do not have. At each level of the thoracic spine, two nerve roots (one on each side) branch into networks of nerves that enable sensation and motor functions on that side of the body. . </span>. Causes of back pain in lung cancer include: 7 A tumor that is placing direct pressure on the structure of the back, most often in the mid to upper back rather than lower back.